之前的Covid - 19感染对登革热患者来说是福还是祸?——印度北部一家三级保健医院的研究

D. Dubey, Swati Agnihotri, S. Vahikar, Shaila Mitra, K. Srivastava, A. Singh, Ravikant Verma
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摘要

目的:通过评估住院天数、血小板输注等指标,研究既往感染对活动性登革热感染患者各项血液学指标及发病率的影响。研究设计:前瞻性研究。学习地点和时间:2022年6月至2022年11月,印度Gorakhpur Baba Raghav Das医学院病理学系。方法:189例活动性登革热感染患者,经IgM检测登革ELISA证实,纳入本前瞻性研究。在入院时记录患者的血液学参数、人口统计资料和临床病理细节。结果:两组患者的平均年龄具有可比性,有COVID - 19病史的登革热患者(A组)为26.93±14.27岁,无COVID - 19病史的登革热患者(B组)为28.52±17.65岁。A组患者平均血小板计数[68200.00±28153.33]高于B组患者[54181.21±31792.06]。A组病死率为2.68%,b组病死率为5%。结论:有COVID-19感染史的个体降低了登革热病死率。然而,我们不能假定登革热与COVID-19感染预后之间存在因果关系。
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Is Previous Covid 19 Infection a Boon or Bane for Dengue Patient? - A Study from a Tertiary Care Hospital in North India
Aims: To study the impact of past COVID 19 infections on various hematological parameters and morbidity in patients with active dengue infection by assessing days of hospital stay, platelet transfusion etc. Study Design: Prospective study. Place and Duration of Study: Department of Pathology, Baba Raghav Das Medical college, Gorakhpur, India between June 2022 to November 2022. Methodology: 189 patients with active dengue infection, proven on Dengue ELISA for IgM detection, were included in this prospective study. Hematological parameters along with demographic profiles and clinicopathological details were recorded for the patients at the time of admission. Results: The mean age was comparable between the two groups, dengue patients with history of COVID 19 (Group A) being 26.93±14.27 years and dengue patients with no history of COVID 19 (Group B) being 28.52±17.65 years. Group A patients were found to have higher mean platelet count [68200.00±28153.33] than Group B patients [54181.21±31792.06]. The fatality rate was 2.68% in the Group A patients and 5% in the group B. Conclusion: Our research indicates that individuals with a history of COVID-19 infection have reduced dengue mortality. However, we cannot presume a causal association between dengue and COVID-19 infection prognosis.
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