{"title":"尼日利亚哮喘患者吸入沙丁胺醇前后对二氧化碳的通气反应。","authors":"O O Elegbeleye, A O Afonja, D Femi-Pearse","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Patterns of response to carbon dioxide (CO2) inhalation in 12 Nigerian asthmatic patients before and after salbutamol aerosol inhalation are described. Ventilatory response to CO2 inhalation follows three patterns, viz,(1) an increase; (2) a decrease; (3) no change in response. While most of our subjects showed substantial improvement in forced expiratory volume in one second (FEV1) following bronchodialator therapy, there was no corresponding change in ventilatory response to CO2. On the whole. the mean values of the slope of response to CO2 inhalation of the asthmatics before and after bronchodilator were not significantly different from values obtained in normal patients in our laboratory.</p>","PeriodicalId":22995,"journal":{"name":"The South African journal of medical sciences","volume":"40 1","pages":"21-5"},"PeriodicalIF":0.0000,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ventilatory response to carbon dioxide in Nigerian asthmatics before and after aerosol salbutamol inhalation.\",\"authors\":\"O O Elegbeleye, A O Afonja, D Femi-Pearse\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Patterns of response to carbon dioxide (CO2) inhalation in 12 Nigerian asthmatic patients before and after salbutamol aerosol inhalation are described. Ventilatory response to CO2 inhalation follows three patterns, viz,(1) an increase; (2) a decrease; (3) no change in response. While most of our subjects showed substantial improvement in forced expiratory volume in one second (FEV1) following bronchodialator therapy, there was no corresponding change in ventilatory response to CO2. On the whole. the mean values of the slope of response to CO2 inhalation of the asthmatics before and after bronchodilator were not significantly different from values obtained in normal patients in our laboratory.</p>\",\"PeriodicalId\":22995,\"journal\":{\"name\":\"The South African journal of medical sciences\",\"volume\":\"40 1\",\"pages\":\"21-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The South African journal of medical sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The South African journal of medical sciences","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ventilatory response to carbon dioxide in Nigerian asthmatics before and after aerosol salbutamol inhalation.
Patterns of response to carbon dioxide (CO2) inhalation in 12 Nigerian asthmatic patients before and after salbutamol aerosol inhalation are described. Ventilatory response to CO2 inhalation follows three patterns, viz,(1) an increase; (2) a decrease; (3) no change in response. While most of our subjects showed substantial improvement in forced expiratory volume in one second (FEV1) following bronchodialator therapy, there was no corresponding change in ventilatory response to CO2. On the whole. the mean values of the slope of response to CO2 inhalation of the asthmatics before and after bronchodilator were not significantly different from values obtained in normal patients in our laboratory.
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