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引用次数: 29

摘要

剪接系统的概念是由Tom Head(1987)提出的,目的是模拟在特定类别的限制性内切酶同时影响下双链DNA分子的重组行为。然而,对于三维空间弦中三维(宏观)分子的复杂(生物)化学过程的建模,结果证明或多或少是不充分的对象。因此,在本文中,作者建议图作为更合适的对象来建模这类过程,并介绍了图拼接系统。文中以DNA剪接为例,说明了该方法的适用性。作者展示了图上的正则图拼接系统和弦上的拼接系统之间的关系,并表明他的新模型允许他在统一的框架内描述弦上的拼接系统以及圆弦上的拼接系统。
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Splicing systems on graphs
The notion of splicing systems has been introduced by Tom Head (1987) in order to model the recombinational behaviors of double-stranded DNA molecules under the simultaneous influence of specified classes of restriction enzymes. Yet for modelling complex: (bio)chemical processes of three-dimensional (macro)molecules in the three-dimensional space strings turn out to be more or less inadequate objects. Hence in this paper the author suggests graphs as more suitable objects for modelling such processes and introduces graph splicing systems. An illustrating example from the area of DNA splicing is elaborated in order to show the suitability of the new approach. The author exhibits the relation between regular graph splicing systems on graphs and splicing systems on strings and shows that his new model allows him to describe splicing systems on strings as well as on circular strings within a uniform framework.<>
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