{"title":"醋酸铑对阿拉伯糖胞嘧啶(NSC-63878)脱胺反应的抑制作用","authors":"S H Lee, D L Chao, J L Bear, A P Kimball","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The nobel metal \"cage\" complex, rhodium(II) acetate, was found to inhibit the deamination of the fraudulent nucleoside, arabinosylcytosine. Potent inhibition of a purified cytidine deaminase from mouse kidney was observed when either cytidine or arabinosylcytosine was used as substrate.</p>","PeriodicalId":9510,"journal":{"name":"Cancer chemotherapy reports","volume":"59 3","pages":"661-3"},"PeriodicalIF":0.0000,"publicationDate":"1975-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Inhibition of Deamination of Arabinosylcytosine (NSC-63878) by Rhodium(II) Acetate.\",\"authors\":\"S H Lee, D L Chao, J L Bear, A P Kimball\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The nobel metal \\\"cage\\\" complex, rhodium(II) acetate, was found to inhibit the deamination of the fraudulent nucleoside, arabinosylcytosine. Potent inhibition of a purified cytidine deaminase from mouse kidney was observed when either cytidine or arabinosylcytosine was used as substrate.</p>\",\"PeriodicalId\":9510,\"journal\":{\"name\":\"Cancer chemotherapy reports\",\"volume\":\"59 3\",\"pages\":\"661-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer chemotherapy reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer chemotherapy reports","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Inhibition of Deamination of Arabinosylcytosine (NSC-63878) by Rhodium(II) Acetate.
The nobel metal "cage" complex, rhodium(II) acetate, was found to inhibit the deamination of the fraudulent nucleoside, arabinosylcytosine. Potent inhibition of a purified cytidine deaminase from mouse kidney was observed when either cytidine or arabinosylcytosine was used as substrate.