{"title":"融合酶及多肽对融合蛋白影响的研究进展","authors":"Chunling Ma, Fang Chen, Li Wang","doi":"10.23977/fbb2020.021","DOIUrl":null,"url":null,"abstract":"Fusion enzyme refers to a comprehensive enzyme binding body composed of two or more independent enzymes or domains. It is mainly obtained through the connection of two or more enzymes, which largely retains the function of several domains and is an efficient protein binding body. Recently, with the development of fusion protein technology, the research on the function of fusion enzyme has become a hot spot. Scientists believe that there is a need for the natural evolution of fusion proteins with linkers. In the process of building fusion enzymes, the introduction of linkers can avoid the interference of different domains in the process of protein folding and catalysis, so as to achieve the efficient expression of fusion enzyme.","PeriodicalId":376375,"journal":{"name":"2020 2nd International Symposium on the Frontiers of Biotechnology and Bioengineering (FBB 2020)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research Progress of Fusion Enzyme and the Effect of Peptide on Fusion Protein\",\"authors\":\"Chunling Ma, Fang Chen, Li Wang\",\"doi\":\"10.23977/fbb2020.021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Fusion enzyme refers to a comprehensive enzyme binding body composed of two or more independent enzymes or domains. It is mainly obtained through the connection of two or more enzymes, which largely retains the function of several domains and is an efficient protein binding body. Recently, with the development of fusion protein technology, the research on the function of fusion enzyme has become a hot spot. Scientists believe that there is a need for the natural evolution of fusion proteins with linkers. In the process of building fusion enzymes, the introduction of linkers can avoid the interference of different domains in the process of protein folding and catalysis, so as to achieve the efficient expression of fusion enzyme.\",\"PeriodicalId\":376375,\"journal\":{\"name\":\"2020 2nd International Symposium on the Frontiers of Biotechnology and Bioengineering (FBB 2020)\",\"volume\":\"32 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2020 2nd International Symposium on the Frontiers of Biotechnology and Bioengineering (FBB 2020)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23977/fbb2020.021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2020 2nd International Symposium on the Frontiers of Biotechnology and Bioengineering (FBB 2020)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23977/fbb2020.021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Research Progress of Fusion Enzyme and the Effect of Peptide on Fusion Protein
Fusion enzyme refers to a comprehensive enzyme binding body composed of two or more independent enzymes or domains. It is mainly obtained through the connection of two or more enzymes, which largely retains the function of several domains and is an efficient protein binding body. Recently, with the development of fusion protein technology, the research on the function of fusion enzyme has become a hot spot. Scientists believe that there is a need for the natural evolution of fusion proteins with linkers. In the process of building fusion enzymes, the introduction of linkers can avoid the interference of different domains in the process of protein folding and catalysis, so as to achieve the efficient expression of fusion enzyme.