[营养性贫血中红细胞磷酸化化合物的水平(作者译)]。

A Floridi, A Morelli, M Floridi
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引用次数: 0

摘要

本文用自动离子交换色谱法测定了2例低血量缺铁性贫血患者和4例大细胞性叶酸缺乏性贫血患者的红细胞磷酸化化合物。在检查营养性贫血的情况下,已观察到糖醇磷酸化化合物水平的显著变化。与临床健康人相比,贫血患者的总酸溶性磷酸盐含量明显增加。2、3 DPG、F1、6DP、R5P、G1、6DP、IMP红细胞含量显著升高。相反,ATP红细胞浓度在所有患者中均明显下降。
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[Level of red blood cell phosphorilated compounds in nutritional anemias (author's transl)].

This paper deals with the determination of red blood cell phosphorilated compounds, by automated ion exchange chromatography, in clinically healthy subjects, in two patients with hypochomic iron deficiency anemia and in four patients with macrocytic folic acid deficiency anemia. In the cases of nutritional anemia examined significant variations in the level of glycolitic phosphorilated compounds have been observed. The total acid-soluble phosphate content presents a marked increase in patients with anemia, compared with clinically healthy subjects. Very high increase in the 2,3 DPG, F1, 6DP, R5P, G1, 6DP and IMP red blood cell content is observed. On the contrary, ATP red blood cell concentration presents a marked decrease in all the patients.

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