软骨肉瘤是一种多面性实体

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摘要

软骨肉瘤(Chondrosarcoma, CS)占所有骨原发恶性肿瘤的20-27%,多见于老年人群[1]。它可能是原发性或继发性的,发生在第二至第五十年。长骨尤其是干骺端是最常见的部位。轴骨,头骨,下颚,手和脚的小骨头是其他可能涉及的部位。虽然罕见,但骨骼外CS可发生在身体的任何部位。传统的CS分为初级CS和次级CS。原发性软骨肉瘤可发生在髓内或皮质旁。继发性CS起源于骨软骨瘤或内软骨瘤。非常规CS为透明细胞、黏液样、间充质、骨外和去分化。这些肿瘤通常分布在长骨(45%)或骨盆(25%)。脊柱(7%)、肩胛骨(5%)、颈椎(6-7%)、颅面骨(2%)、手和脚很少受到影响[2]。
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Chondrosarcoma-A Multi-Faceted Entity
Chondrosarcoma (CS) accounts for 20-27% of all primary malignant tumors of bone mostly seen in older age group [1]. It may be primary or secondary occurring in 2nd to 5th decade. The long bones especially the metaphysis are the most common sites. Axial skeleton, skull, jaw, small bones of hand and feet are other sites that can be involved. Though rare, extraskeletal CS may occur anywhere in the body. The conventional CS are primary or secondary. Primary chondrosarcoma may be intramedullary or Juxtacortical. Secondary CS arises from Osteochondroma or Enchondroma. Nonconventional CS are clear cell, myxoid, mesenchymal, extraskeletal, and dedifferentiated. Usual distribution of these tumors is long bones (45%) or pelvis (25%). The spine (7%), scapula (5%), cervical spine (6-7%), craniofacial bones (2%), hand and foot are rarely affected [2].
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