CA-72.4肿瘤标志物利用与肿瘤检测的综合研究:基于卫生部数据的分析

Ş. Birinci, M. M. Ülgü
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摘要

背景:本研究旨在探讨CA 72.4肿瘤标志物在癌症诊断中的相关性和利用,重点关注胃肠道肿瘤和卵巢癌,基于卫生部的数据。材料和方法:我们对卫生部五年来的健康记录进行了回顾性分析。统计分析了包括性别、年龄和临床服务请求在内的各种人口统计数据。CA 72.4肿瘤标志物的参考范围超出率、诊断次数、肿瘤诊出率和费用分配是评估的关键方面。结果:分析显示,多年来对ca72.4测试的要求显著增加。还观察到,随着时间的推移,癌症检出率略有增加,CA 72.4阳性的患者比例较高,主要是在诊断前要求的。对该测试要求最高的是内科肿瘤诊所。此外,还观察到性别和年龄组在癌症诊断的患病率中起着重要作用。结论:我们的研究表明,使用CA 72.4作为肿瘤标志物可能是有价值的,特别是在某些类型癌症的检测中。然而,CA 72.4检测阳性与明确癌症诊断之间的相关性需要进一步研究,因为该标志物的敏感性和特异性仍然存在争议。尽管存在一定的局限性,但本研究对CA 72.4在当前医疗保健环境中的效用提供了实质性的见解。
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A Comprehensive Study of the CA-72.4 Tumor Marker Utilization and Cancer Detection: Analysis Based on Ministry of Health Data
Background: This study aims to explore the relevance and utilization of the CA 72.4 tumor marker in cancer diagnosis, with a particular focus on gastrointestinal tumors and ovarian cancer, based on data from the Minis-try of Health. Materials and Methods: We conducted a retrospective analysis of health records from the Ministry of Health spanning over five years. The data, consisting of various demographics, including gender, age, and clinical service requests, was statistically analyzed. The rates of reference range exceedance for the CA 72.4 tumor marker, diagnosis times, the ratio of cancer diagnosis, and the cost distribution were among the key aspects evaluated. Results: The analysis revealed a significant increase in the request for CA 72.4 tests over the years. It was also observed that cancer detection rates slightly increased over time, with a higher percentage in patients testing positive for CA 72.4, primarily requested before diagnosis. The highest requests for the test were made by the Medical Oncology clinic. Furthermore, it was observed that gender and age groups played significant roles in the prevalence of cancer diagnoses. Conclusions: Our study indicates that the use of CA 72.4 as a tumor marker could be valuable, especially in the detection of certain types of cancer. However, the correlation between a positive CA 72.4 test and a definitive cancer diagnosis requires further investigation, as the sensitivity and specificity of this marker are still subjects of debate. Despite certain limitations, this study offers substantial insights into the utility of CA 72.4 in the current healthcare setting.
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