狂犬病传播动力学与控制的数学分析

Suleman Adamu Bukari, Baba Seidu, M. I. Daabo
{"title":"狂犬病传播动力学与控制的数学分析","authors":"Suleman Adamu Bukari, Baba Seidu, M. I. Daabo","doi":"10.3126/jnms.v5i2.50021","DOIUrl":null,"url":null,"abstract":"Rabies is a dangerous disease that kills many people than any other communicable disease and yet it is underrated. This results from the little knowledge on the myriad ways of transmission of the virus. A deterministic model is proposed to study the spread of the rabies virus in both domestic dogs (Canis familiaries) and humans (Homo sapiens). We elaborately studied the spread of the rabies virus from dogs to-dogs, dogs-to-humans and for the first time, humans-to-humans. Sensitivity analysis is performed to determine the influence of various parameters on the transmission of rabies the most. The rabies-free equilibrium and the endemic equilibrium points were determined and the conditions under which the equilibria are stable were also obtained. The stability conditions provide the conditions under which the disease will persist or get to be eradicated. Numerical solutions of the model were obtained using the ode45 routine in MATLAB. The study demonstrated that for rabies to be eradicated, the rate at which dogs are recruited must be decreased, culling of exposed and infected dogs should be increased and mass vaccination of the dog population should be targeted.","PeriodicalId":401623,"journal":{"name":"Journal of Nepal Mathematical Society","volume":"38 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mathematical Analysis of Rabies Transmission Dynamics and Control\",\"authors\":\"Suleman Adamu Bukari, Baba Seidu, M. I. Daabo\",\"doi\":\"10.3126/jnms.v5i2.50021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Rabies is a dangerous disease that kills many people than any other communicable disease and yet it is underrated. This results from the little knowledge on the myriad ways of transmission of the virus. A deterministic model is proposed to study the spread of the rabies virus in both domestic dogs (Canis familiaries) and humans (Homo sapiens). We elaborately studied the spread of the rabies virus from dogs to-dogs, dogs-to-humans and for the first time, humans-to-humans. Sensitivity analysis is performed to determine the influence of various parameters on the transmission of rabies the most. The rabies-free equilibrium and the endemic equilibrium points were determined and the conditions under which the equilibria are stable were also obtained. The stability conditions provide the conditions under which the disease will persist or get to be eradicated. Numerical solutions of the model were obtained using the ode45 routine in MATLAB. The study demonstrated that for rabies to be eradicated, the rate at which dogs are recruited must be decreased, culling of exposed and infected dogs should be increased and mass vaccination of the dog population should be targeted.\",\"PeriodicalId\":401623,\"journal\":{\"name\":\"Journal of Nepal Mathematical Society\",\"volume\":\"38 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nepal Mathematical Society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3126/jnms.v5i2.50021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nepal Mathematical Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3126/jnms.v5i2.50021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

狂犬病是一种危险的疾病,比任何其他传染病夺去许多人的生命,但它却被低估了。这是由于人们对病毒的无数传播途径知之甚少。提出了一种确定性模型来研究狂犬病病毒在家养狗(犬科)和人类(智人)中的传播。我们仔细研究了狂犬病病毒在狗与狗、狗与人之间的传播,并首次研究了人与人之间的传播。通过敏感性分析确定各参数对狂犬病传播的影响最大。确定了无狂犬病平衡点和地方性平衡点,并得到平衡点稳定的条件。稳定条件提供了疾病持续存在或被根除的条件。利用MATLAB中的ode45程序对该模型进行了数值求解。研究表明,要根除狂犬病,必须降低犬只招募率,增加对暴露和感染犬只的扑杀,并针对犬只群体进行大规模疫苗接种。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Mathematical Analysis of Rabies Transmission Dynamics and Control
Rabies is a dangerous disease that kills many people than any other communicable disease and yet it is underrated. This results from the little knowledge on the myriad ways of transmission of the virus. A deterministic model is proposed to study the spread of the rabies virus in both domestic dogs (Canis familiaries) and humans (Homo sapiens). We elaborately studied the spread of the rabies virus from dogs to-dogs, dogs-to-humans and for the first time, humans-to-humans. Sensitivity analysis is performed to determine the influence of various parameters on the transmission of rabies the most. The rabies-free equilibrium and the endemic equilibrium points were determined and the conditions under which the equilibria are stable were also obtained. The stability conditions provide the conditions under which the disease will persist or get to be eradicated. Numerical solutions of the model were obtained using the ode45 routine in MATLAB. The study demonstrated that for rabies to be eradicated, the rate at which dogs are recruited must be decreased, culling of exposed and infected dogs should be increased and mass vaccination of the dog population should be targeted.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Transmission Dynamics of Dengue Disease in the Rupandehi District of Nepal Delta Power Transformation: A New Family of Probability Distributions Mathematical Modeling of Pollutants Dispersion in the Atmosphere On Certain Statistical Convergence Criteria for Martingale Sequences via Deferred Ces`aro Mean with Some Applications Tandem Queue and Its Applications in the Production of Bi-layer Tablets
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1