用于生物组织破坏的高频电磁系统

S. V. Belavskaya, L. I. Lisitsyna, A. Kuzmin, Ekaterina K. Vinskaya, L. G. Navrotsky, V. Razinkin, A. A. Blokhin
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摘要

考虑了在高频范围内使用冲击电磁辐射消融生物组织(软组织和高密度组织)的可能性。对比分析了电磁辐射在微波范围(MWA)和高频范围(HF)进行烧蚀的特性。实验结果表明,两种方法的烧蚀特性非常接近。提出了无创和有创两种方法的高频消融技术,并进行了实验测试。提出了生物组织破坏程度的激光控制方法,提高了控制的可靠性。实验使用由本工作作者参与创建的固定频率为13.56 MHz的高频发生器进行。使用高频发生器,在不使用闭合电路的情况下,通过针状发射器(医用钢)对生物组织产生影响。用猪皮和牛的肌肉作为活组织检查。对暴露物进行灼烧、切除、凝固处理。结果表明,在HF烧蚀(HF)下,组织被加热到120°c,使用德国制造的具有热成像仪功能的万用表来研究曝光焦点的温度。这种万用表可以捕获放电位置的最高温度区域,当发射器接近皮肤并将皮肤加热到一定温度时,就会发生热烧蚀。结果表明,高频消融几乎不影响周围组织。研制并实施了用于实验研究的高频电磁系统。在此基础上,提出了利用俄罗斯高频发生器烧蚀生物组织的设想。
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A high-frequency electromagnetic system for biological tissues destruction
The possibility of using an impacting electromagnetic radiation in the high-frequency range for ablation of biological tissues (soft and high density) is considered. A comparative analysis of the characteristics of ablation performed using electromagnetic radiation of the microwave range (microwave ablation method (MWA)) and high-frequency (HF) range is given. It was experimentally revealed that the characteristics of ablation performed by both methods are close to each other. HF ablation techniques performed by non-invasive and invasive methods are proposed and experimentally tested. Laser control of the degree of destruction of biological tissue is proposed which increases the reliability of control. The experiments were carried out using a high-frequency generator at a fixed frequency of 13.56 MHz created with the participation of the authors of this work. The use of an HF generator provided an effect on a biological tissue with a needle-type emitter (medical steel), without using a closed electrical circuit. Pig skin and muscles of cattle were used as biopsies. The processes of burning out the object of exposure, resection and coagulation were performed. It is shown that with HF ablation (HF), the tissue is heated to 120 ° C. A multimeter with the function of a thermal imager CEM DT-898 manufactured in Germany was used to study the temperature in the focus of exposure. This multimeter allows capturinge the area with the maximum temperature at the place of discharge, which occurs when the emitter approaches the skin and heats the skin to a certain temperature, as a result of which thermal ablation occurs. It was revealed that HF ablation occurs practically without affecting the surrounding tissues. A high-frequency electromagnetic system for conducting experimental studies has been developed and implemented. Based on the results of the work, it is proposed to ablate biological tissue using Russian HF generators.
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