磷脂在BK病毒感染和血凝中的作用。

Microbiologica Pub Date : 1992-10-01

L Sinibaldi, P Goldoni, V Pietropaolo, L Cattani, C Peluso, C Di Taranto

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引用次数: 0

摘要

通过竞争结合实验和磷脂酶处理易感细胞，研究了磷脂在BK病毒感染和血凝中的作用。从Vero细胞中提取的磷脂和一些商业磷脂显示出抑制BK病毒感染和血液凝集的活性。用磷脂酶处理Vero细胞影响了BK病毒的结合，但在酶处理的细胞中添加磷脂恢复了它们对病毒感染和血凝的敏感性。

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Role of phospholipids in BK virus infection and haemagglutination.

The role of phospholipids in BK virus infection and haemagglutination was studied by competition binding experiments and by treatment of susceptible cells with phospholipases. Phospholipids extracted from Vero cells and some commercial phospholipids showed an inhibiting activity on both BK virus infectivity and haemagglutination. The treatment of Vero cells with phospholipases affected the binding of BK virus, but the addition of phospholipids to enzyme-treated cells restored their susceptibility to both viral infectivity and haemagglutination.

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Microbiologica

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