对选定医院儿童中与类固醇治疗有关的常见感染进行评估,以便编写一份资料小册子

Priya Vijay Bhorge
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摘要

皮质类固醇是一种有效的药物,广泛用于治疗许多炎症和自身免疫性疾病。它们已被用于各种危及生命和致残的情况,并挽救或改善了许多生命。然而,它们会对不同的身体系统产生许多副作用。皮质类固醇抑制免疫系统,增加对感染的易感性。常规剂量的皮质类固醇1-2周可使患者容易感染。因此,本研究旨在评估与类固醇治疗相关的常见感染,这些感染通常与长期使用这些药物有关,并为患者监测和预防和管理这些感染提供实用建议。对于本研究,定量研究方法被认为是合适的。一项研究设计为非实验性探索性设计。本研究在选定的城市医院进行。选择的样本是在医院接受类固醇治疗的儿童,符合包容性和排他性标准。样本量为60例,采用非概率目的抽样。发现自结构感染评估清单格式是评估儿童中与类固醇治疗相关的常见感染的最合适工具。数据分析采用描述性统计和推断性统计,以呼吸道感染为主,占38.3%,其次为皮肤感染,占25%,胃肠道感染占15%,尿路感染占1.7%。类固醇治疗的持续时间和父母的教育程度与儿童胃肠道感染有显著的关系。发现儿童发育阶段和类固醇治疗持续时间与儿童呼吸道感染有显著相关性。没有发现人口统计学变量与儿童尿路感染有显著关联。儿童的发育阶段和父母的教育程度与儿童胃肠道感染有显著的相关性。
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Assessment of common infections related to steroidal treatment among children in selected hospitals, in view to develop an information booklet
Corticosteroids are potent medications that have been extensively used to treat many inflammatory and autoimmune conditions. They have been used in a variety of life-threatening and disabling conditions and have saved or improved many lives. However, they cause numerous side effects on various body systems. Corticosteroids inhibit the immune system and increase susceptibility to infections. A regular dose of corticosteroids for 1-2 weeks can make the patient prone to infection.Therefore the study was conducted to assess the common infections related to steroidal treatment which are commonly associated with long-term use of these agents and provide practical recommendations for patient monitoring and the prevention and management of these infections. For this study, quantitative research approach was considered appropriate. A research design was Non-experimental exploratory design. This study was conducted in selected hospitals of city. The samples selected was Children on steroidal treatment admitted in hospitals who meet the inclusive and exclusive criteria. Sample size was 60 and non- probability purposive sampling was used. Self-structured infection assessment checklist format was found to be the most appropriate instrument to assess common infections related to steroidal treatment among children. Descriptive and inferential statistics used for data analysis Majority 38.3% of them had respiratory tract infection followed by 25% of them had skin infection, 15% of the children had gastrointestinal tract infection and 1.7% of them had Urinary tract infection. Duration of steroidal treatment and education of the parents were found to have significant association with gastrointestinal tract infection among children. Developmental stage of child and duration of steroidal treatment were found to have significant association with respiratory tract infection among children. None of the demographic variable was found to have significant association with urinary tract infection among children. Developmental stage of child and Education of the parents were found to have significant association with gastrointestinal tract infection among children.
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