衰老大鼠小肠酶转运特性研究。

A M Ugolev, V V Egorova, N N Iezuitova, N M Timofeeva, L V Gromova, B Z Zaripov
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引用次数: 0

摘要

研究表明,衰老伴随着小肠碳水化合物酶、二肽酶和碱性磷酸酶活性水平的变化。这些变化在正常情况下和小肠手术后都会发生。随着年龄的增长,无论功能负荷的增加或减少,小肠的同型发育能力都会下降。随着胃肠道老化,不仅水解过程受到干扰,而且运输过程也受到干扰:特别是大鼠肠粘膜制剂中葡萄糖积累的减速。在老年大鼠中,一些酶的调节特性也发生了变化。
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[The enzyme-transport characteristics of the small intestine of rats during aging].

Ageing was shown to be accompanied by changes of the activity levels of the small intestine's carbohydrases, dipeptidases, and alkaline phosphatases. The changes occurred both under normal conditions and after operations on the small intestine. In ageing, the small intestine's capacity for the homeomorphosis decreases irrespective of either increase or decrease in the functional loading. The age involution of the gastrointestinal tract is followed by disturbances not only in hydrolytic processes but in transport those as well: particularly deceleration of glucose accumulation in preparations of the rat intestine mucose. Regulatory properties of some enzymes were changed, too, in old rats.

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