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引用次数: 0

摘要

以2h -吡嗪-3- 1为唯一碳源的细菌可以从园林土壤中分离出来。这种细菌可被鉴定为分枝杆菌。测定DNA的gc含量为61.4%。可分离鉴定出典型分枝杆菌素。几种方法均未检测到降解途径的中间体。与2H-pyridazin-3-one结构相似的不同化合物的生长研究表明,该分枝杆菌菌株对该化合物具有很高的特异性。
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Abbau von 2H-pyridazin-3-on durch ein Mycobacterium

Bacteria growing on 2H-pyridazin-3-one as sole carbon source could be isolated from garden soil. The bacteria could be identified as a mycobacterium. The GC-content of the DNA was determined as 61,4%. Typical mycobactins could be isolated and identified. With several methods no intermediate of the degradative pathway could be detected.

Growth studies with different compounds showing structural analogy to 2H-pyridazin-3-one suggest, that the mycobacterium strain exhibits a high specificity towards this compound.

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