禽分枝杆菌复合体与hiv感染者免疫重建炎症综合征相关

R. Cernat, I. Dumitru, C. Șerban
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摘要

近年来,由于高效抗逆转录病毒疗法(HAART)的引入和克拉霉素预防的开始,艾滋病毒感染者中鸟分枝杆菌复合体(MAC)病的发病率显著下降。我们报告一个晚期艾滋病患者的病例,有广泛性淋巴结病和消化系统症状,诊断为弥散性MAC,诊断是基于腋窝淋巴结和肠道活检的结果。考虑到MAC诊断的时间与最近引入抗逆转录病毒(ARV)治疗有关,我们考虑在阿奇霉素、乙胺丁醇和莫西沙星治疗下进展良好的免疫重建炎症综合征(IRIS)。
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MYCOBACTERIUM AVIUM COMPLEX ASSOCIATED IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME IN HIV- INFECTED PATIENT
The incidence of Mycobacterium avium Complex (MAC) Disease in HIV-infected individuals has significantly decreased in recent years due to the introduction of Highly Active Antiretroviral Therapy (HAART) and the initiation of Clarithromycin prophylaxis. We present the case of a patient with advanced AIDS, with generalized lymphadenopathy and digestive symptoms, diagnosed with disseminated MAC, a diagnosis which was based on the results obtained from axillary lymph node and intestinal biopsies. Considering the time of the MAC diagnosis in relation to the recent introduction of antiretroviral (ARV) therapy, we considered immune reconstitution inflammatory syndrome (IRIS) with good evolution under azithromycin, ethambutol and moxifloxacin treatment.
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