Is Zero-Balance Ultrafiltration an Effective Clinical Method for SIRS Prevention During Extracorporeal Circulation in Adults Heart Diseases Correction?

Background: Ultrafiltration, which is currently considered as a standard method to remove the excess water administered during cardiopulmonary bypass (CPB), aims to minimize the adverse effects of hemodilution, such as tissue edema and blood transfusion. Three ultrafiltration techniques can be used before, during and after CPB procedure, including conventional ultrafiltration (CUF), zero-balance ultrafiltration (Z-BUF), and modified ultrafiltration (MUF) at the end of CPB. The aim of study: The present research attempts to revise the efficiency of Z-BUF ultrafiltration method, laboratory results, and clinical impacts. Material and methods: 94 adults (54 men and 40 women) with acquired heart diseases undergoing a single cardiac surgical procedure in condition of cardiopulmonary bypass (clamp aortic 89, 9± 38, 8 min. and pump 135,14 ± 45,17 min.) were divided into 3 groups. 1st group (no ultrafiltration) - 34 patients with classic cardiac surgery, 2nd with the use of zero-balance ultrafiltration (ZBUF) group - 37 patients with classic cardiac surgery, and 3rd group ZBUF with mini invasive cardiac surgery - 23 patients.