布鲁氏菌病,在流行地区治疗Covid-19后引起肌肉和关节疼痛的罕见原因

S. Aslan
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摘要

摘要目的:我们旨在了解布鲁氏菌病流行地区2019冠状病毒病(Covid-19)后持续出现的症状中是否存在肌肉-关节疼痛和不适。方法:选取2020年4月1日后在我院诊断为Covid-19且持续存在肌肉关节疼痛的pcr阳性患者15例,布鲁氏菌凝集和/或库姆斯凝集1/160及以上检测阳性。结果:男性6例(40%),女性9例(60%)。男性年龄在31-69岁之间,中位数为52,而女性年龄在38-57岁之间,中位数为43。肌肉关节疼痛、不适、疲劳、发热和出汗是常见的症状。在新冠病毒感染后的7至220天期间,出现症状的时间不等。结论:我们认为在流行地区诊断为Covid-19的患者,治疗后以肌肉关节疼痛和不适症状就诊的患者应考虑布鲁氏菌病的鉴别诊断。
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Brucellosis, a rare cause of muscle and joint pain following Covid-19 treatment in endemic regions
ABSTRACT Objective: We aimed to show the presence of muscle-joint pain and malaise among the symptoms persisting following Covid-19 disease in regions where brucellosis is endemic. Methods: Fifteen PCR-positive patients diagnosed with Covid-19 after 1 April, 2020, in our hospital and with persisting muscle-joint pain, and testing positive with Brucella agglutination and/or Coombs agglutination 1/160 or above were included in the study. Results: Six (40%) of the patients in the study were male and nine (60%) were female. Males were between the ages of 31-69 and had a median value of 52, while females were between the ages of 38-57 and had a median value of 43. Muscle-joint pain, malaise, fatigue, fever, and sweating were frequently seen symptoms. Time to onset of symptoms in the post-Covid period ranged between seven and 220 days. Conclusion:We think that brucellosis should be considered in the differential diagnosis of patients diagnosed with Covid-19 in endemic regions ad presenting to hospital with symptoms of muscle-joint pain and malaise after treatment.
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