The role of MR spectroscopy in the differential diagnosis of anaplastic glioma

The role of biomarkers for detecting tumors has aroused interest in their use for diagnostics as well. Biomarkers can be isolated from biological fluids, such as blood, cerebrospinal fluid, and urine. Apparently, the most promising is the study of blood plasma and serum, which are isolated from whole blood and are the most studied biological resources for the potential detection of molecular markers. This direction includes studies to identify immunological or biochemical biomarkers of the presence of tumors in the cerebrospinal fluid or in the blood of patients. Infrared spectroscopy of plasma and blood serum of patients with tumors is more promising in terms of identifying not only individual mRNAs as markers of gliomas, but also fats, proteins, and carbohydrates. The study of the profile of metabolites in blood plasma by methods of the recently emerged science of "metabolomics" has good prospects. This gives information about the biochemical processes occurring in tumors and provides knowledge for determining the treatment tactics for recurrent growth.