人乳头瘤病毒基因型共感染和健康风险-罗马尼亚东部人口的初步研究

Codrin Gheorge, Schroder Verginica, Stoicescu Ramona, Honcea Adina, D. Irina
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引用次数: 0

摘要

该研究旨在确定不同年龄人群中HPV感染和合并感染的程度,以评估与罗马尼亚人口缺乏免疫相关的风险。在本研究中,我们正在研究罗马尼亚Constanța Prodiagnostic分析实验室在2018-2019年期间分析的37例疑似HPV感染病例中存在的不同类型HPV株的患病率和关系。在案例研究分析的总人数中,45.94%(37人中有17人)的HPV感染检测呈阳性。按风险类别对菌株出现频率进行分析,高风险菌株出现频率最高,为48%,其次是未知风险菌株(44%)和低风险菌株(8%);按年龄分析,记录的最大感染率属于23至34岁年龄组。菌株和50%频率之间的关联表明了感染的一个重要方面,以及诊断和治疗的重要数据,并涉及对具有这种关联的患者进行更严格的监测,风险随着关联而增加。
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HPV GENOTYPES COINFECTIONS AND HEALTH RISK - PRELIMINARY STUDY OF THE EAST ROMANIAN POPULATION
The study aims to identify the degree of infection and co-infection with HPV strains in people of different ages, to assess the risk associated with lack of immunization of the Romanian population. In this study we are looking at the prevalence and relationship of the different types of HPV strains present in the 37 cases with suspected HPV infection that were analyzed, in the period 2018-2019, within the Prodiagnostic analysis laboratory, in Constanța, Romania. Of the total number of people analyzed for the case study, 45.94% (17 out of 37) tested positive for HPV infection. The analysis of the frequency of strains by risk categories shows that the highest percentage was 48% in the case of high-risk strains, followed by the percentage of frequency of strains with unknown risk (44%) and that of low-risk strains (8 %); The analysis by age indicates the maximum infection rate recorded belonging to the age group between 23 and 34 years. The association between strains and the 50% frequency indicates an important aspect of the infection as well as important data for diagnosis and treatment and involves more rigorous monitoring of patients with such associations, the risk increases with the associations.
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