光学相干断层成像和光声成像在体内检测成年斑马鱼脑光学特性

Yintao Lan, Weijian Gao, Mengyu Zhou, Jing Huang, Shuqi Gan, Yao Xu, Ting Lu, Yiqing Zhang, Jian Zhang
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引用次数: 0

摘要

动物模型的全脑成像是当前光学领域的一大挑战,尤其是对自由运动动物的全脑成像。本文利用光学相干断层扫描(OCT)和光声显微镜(PAM)对斑马鱼大脑进行了体内高分辨率和长期表征。OCT和PAM的结合在体内对成年斑马鱼大脑复杂结构进行了表征,结果令人满意。
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Optical properties of adult zebrafish brain detected by optical coherence tomography and photoacoustic imaging in vivo
The whole brain imaging of animal models is a major challenge in the current optical field, especially in freely moving animals. In this paper, in vivo high-resolution and long-term characterization of zebrafish brain were achieved with optical coherence tomography (OCT) and photoacoustic microscopy (PAM). The combination of OCT and PAM demonstrated gratifying results in vivo characterization of adult zebrafish brain’s complex structure.
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