粘膜念珠菌感染的诊断和治疗综述

M. Dąbrowska, Monika Sienkiewicz, P. Kwiatkowski, M. Dąbrowski
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引用次数: 4

摘要

白色念珠菌是世界范围内真菌感染的最常见原因。非白色念珠菌在外阴阴道念珠菌病和侵袭性感染中起重要作用。大多数感染病例是内源性的。在患有免疫系统疾病的患者中,这种机会性病原体可引起表面、全身感染和念珠菌病。症状取决于受影响的区域。用抗真菌药物治疗念珠菌病;这些药物包括克霉唑、制霉菌素、氟康唑、伏立康唑、两性霉素B和棘白菌素。耐药性的出现和目前可用的抗真菌药物的副作用正在成为念珠菌感染管理的主要问题。
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Diagnosis and treatment of mucosa Candida spp. infections – a review article
Candida albicans is the most common cause of fungal infections worldwide. Non-albicans Candida species play an important role in vulvovaginal candidiasis and invasive infections. Most cases of infections are endogenous. In case of patients with immune disorders this opportunistic pathogen causes both surface, systemic infections, and candidemia. Symptoms depend on the area affected. Candidiasis are treated with antimycotics; these include clotrimazole, nystatin, fluconazole, voriconazole, amphotericin B, and echinocandins. The emergence of drug resistance and the side effects of currently available antifungals are becoming a major problem in the management of Candida spp. infection.
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