心肌桥接在心肌缺血中的作用:1例报告

A. V. Solov’yeva, A. Gurbanova, Ivan A. Maksimtsev, O. Lazareva, E. A. Maksimtseva
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引用次数: 0

摘要

导读:心肌桥接(MB)被认为是一种良性病理,然而,它的存在往往与心绞痛、心肌梗死、室性心动过速和心源性猝死有关。MB的临床意义是由冠状动脉的动态狭窄决定的,这取决于心脏收缩的速度和强度,仪器方法很难观察到,这影响了及时诊断和早期给予适当治疗。本文报告一例58岁患者冠状动脉床合并损伤的临床病例:前室间动脉(AIVA)的MB引起隧道动脉动态显著狭窄和冠状动脉血流动力学不显著的动脉粥样硬化病变。MB通常位于AIVA中段。冠状动脉造影后确定了冠状动脉床异常的诊断:AIVA的MB导致隧道段狭窄80%,是心绞痛发作的原因。采用药物涂层支架对AIVA进行支架植入。支架植入术的有效性可以参考本病例的一个特殊特征,因为在治疗这种病理时,首选肌切开术和冠状动脉旁路移植术作为更有效的方法。随访时间为7.5年;在AIVA隧道段支架置入术后,心绞痛没有复发。结论:本临床病例证实了MB在心肌缺血发展中的作用。及时诊断冠状动脉血流障碍,成功进行血运重建,并按照目前的临床建议给予适当的药物治疗,预后良好。
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Role of Myocardial Bridging in Myocardial Ischemia: Case Report
INTRODUCTION: Myocardial bridging (MB) is considered a benign pathology, however, its existence is often associated with angina pectoris, myocardial infarction, ventricular tachycardia and sudden cardiac death. The clinical significance of MB is determined by the dynamic stenosis of the coronary artery, which depends on the rate and strength of heart contractions and is poorly visualized by instrumental methods, which impairs timely diagnosis and early administration of the adequate treatment. A clinical case of a combined damage to the coronary bed in a 58-year-old patient is presented: MB of the anterior interventricular artery (AIVA) causing dynamically significant narrowing of the tunnel artery and hemodynamically insignificant atherosclerotic lesion of the coronary arteries. MB was typically located in the mid-segment of the AIVA. The diagnosis of the anomaly of the coronary bed was established after coronary angiography: MB of AIVA led to stenosis of the tunnel segment to 80% and was the cause of angina attacks. Stenting of the AIVA with a drug-coated stent was performed. The effectiveness of the stenting can be referred to a peculiar feature of this case, since in the treatment of this pathology the preference is given to myotomy and coronary artery bypass grafting as more effective methods. The follow-up period was 7.5 years; after stenting of the tunnel segment of the AIVA the anginal attacks did not recur. CONCLUSION: The described clinical case demonstrates the role of MB in the development of myocardial ischemia. With timely diagnosis of the coronary blood flow disorders, successful revascularization and adequate pharmacotherapy in accordance with the current clinical recommendations, the prognosis is good.
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