细胞质微管组装在细胞质中发生改变

Sujata Guha Roy , A.N. Bhisey
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引用次数: 1

摘要

在培养的人二倍体成纤维细胞(MRC-5)和小鼠腹膜巨噬细胞的去核细胞质中,研究了微管组织中心(MTOC)形成的细胞质微管复合体(CMTC)的微管组织成核。两种细胞类型的细胞质都不能组织完整的CMTC。MRC-5细胞中出现异常MT模式,而小鼠巨噬细胞中出现少量短MT。研究提示细胞核可能在CMTC的决定中起作用。
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Cytoplasmic microtubule assembly is altered in cytoplasts

Nucleation of microtubule (MT) organization of the cytoplasmic microtubule complex (CMTC) from the microtubule organizing centres (MTOC) was studied in enucleated cytoplasts of human diploid fibroblast (MRC-5) and mouse peritoneal macrophages in culture. Cytoplasts of both cell types could not organize the complete CMTC. Aberrant MT patterns were seen in MRC-5 cells while mouse macrophages showed occurrence of few short MT. The studies suggest that nucleus may have a role in determining CMTC.

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