遗传调控网络的随机渐近有界性

Mohammad Mohamadian, H. Momeni
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引用次数: 0

摘要

由于生物化学过程在分子水平上的随机性,遗传调控网络具有固有的噪声。它们也受到基因表达之外的外部噪音的影响。本文考虑了具有非消失加性噪声的遗传调控网络,研究了它们的随机渐近有界性。利用itô的微分公式和Lyapunov-Krasovskii泛函,我们得到了系统解被噪声协方差最大值的单调函数有界(期望上)的充分条件。所有这些条件都是用线性矩阵不等式(lmi)来表示的。最后,通过数值算例说明了所提条件的有效性和适用性。
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Stochastic asymptotic boundedness of genetic regulatory networks
Due to the randomness of the biochemical process at the molecular level, genetic regulatory networks are inherently noisy. They are also subjected to extrinsic noises which are external to the gene expression. In this paper, we consider genetic regulatory networks with non-vanishing additive noises and investigate stochastic asymptotic boundedness of them. By using itô's differential formula and Lyapunov-Krasovskii functional, we derive sufficient conditions so that system solution be bounded (in expectation) by a monotone function of the supremum of the covariance of the noise. All these conditions are presented in terms of linear matrix inequalities (LMIs). Finally, Numerical example illustrates the usefulness and applicability of the proposed conditions.
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