妊娠期COVID-19疫苗的供应和使用

Saugat Koirala, S. Pant, B. Chaudhary
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摘要

感染SARS-CoV-2的孕妇更有可能出现严重后果,包括进入ICU、不良心脏和血栓栓塞事件以及早产。怀孕期间的免疫接种有一定的伦理困境,疫苗接种似乎具有挑战性。关于在孕妇中使用基于mRNA的疫苗对抗这种病毒的初步数据是有希望的。最近,RCOG和世卫组织扩大了在孕妇中使用COVID-19疫苗的范围。同样,ACOG还批准在孕妇中使用两种基于mRNA的疫苗和一种基于病毒载体的疫苗。在世界发达地区,孕妇和哺乳期妇女接种疫苗的范围正在实现,这在预防COVID-19感染方面具有良好的前景。然而,发展中国家需要私人利益攸关方、卫生和社会保健组织的关注,以确保人人享有健康权。
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Availability and Use of Vaccines against COVID-19 in Pregnancy
Pregnant women when infected with SARS-CoV-2 infection are more at risk of having severe outcomes including ICU admission, adverse cardiac and thromboembolic events and preterm delivery. Immunization in pregnancy has certain ethical dilemmas and vaccination seems to be challenging. Preliminary data regarding the use of mRNA based vaccines against this virus in pregnant women is promising. Recently, RCOG and WHO have widened the scope of use of vaccines among pregnant women against COVID-19. Similarly, ACOG has also given the go-ahead to the use of two mRNA based and one viral vector based vaccine in pregnant women. The scope of vaccination among pregnant and lactating women being realized in developed part of world is a promising prospect in prevention of COVID-19 infections. However, developing nations require attention from private stakeholders, health and social care organizations to ensure right of health for all.
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