{"title":"辣椒果胶和乙醇的变种","authors":"Widitia Pristifa Darajati, Yani Ambari","doi":"10.36932/jpcam.v3i2.70","DOIUrl":null,"url":null,"abstract":"Cayenne pepper leaf (Capsicum frutescents L) is one of the natural ingredients that contains chemical compounds including saponins, alkaloids, terpenoids, quinones and flavonoids. Saponin and flavonoid compounds in cayenne pepper leaves have a role to stimulate hair growth. So that it can be used to overcome the problem of hair loss, where hair loss often occurs in the community dueto lack of nutritional intake and excessive use of chemicals. To overcome this, this research was carried out which aims to use preparations from natural ingredients of ethanol extract of cayenne pepper leaves which were made into hairtonic preparations with variations of propylene glycol and 96% ethanol Hairtonic formulations used 96% ethanol, menthol, propylene glycol, methyl paraben, propyl paraben, and aquades. Then a physical stability test was carried out to determine at what concentration the hairtonic preparation produced good physical stability. Hairtonic physical stability test was carried out for 14 days of storage with organoleptic results. Brownish orange color in the form of a clear solution and distinctive aroma of cayenne pepper leaf extract, the pH test was from the last cycle Formulation 1: 4.9 then Formulation 2: 5.0 and Formulation 3. : 5.1. Still in the skin pH range of 4.5-6.5, the Viscosity test is from the last cycle of Formulation 1: 1.01 Cps then Formulation 2: 0.95 Cps and Formulation 3: 1.06 Cps. Still in the hair tonic viscosity specification, which is below 5 Cps, in the Specific Gravity test in Formulation 1: 0.9950 gram/ml. then Formulation 2: 0.9951 gram/ml. and Formula 3: 0.9978 gram/ml. Still in the hair tonic viscosity specification, which is ±1 gram/ml. From these results, it can be seen that at concentrations of propylene glycol 10%, 15%, 20% and ethanol 5%, 10%, 15% produced good physical stability","PeriodicalId":433767,"journal":{"name":"Journal of Pharmaceutical Care Anwar Medika","volume":"108 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Formulasi dan Uji Stabilitas Fisik Sediaan Hair Tonic Ekstrak Daun Cabai Rawit (Capsium Frutescent L). Dengan Variasi Propilenglikol Dan Etanol 96%\",\"authors\":\"Widitia Pristifa Darajati, Yani Ambari\",\"doi\":\"10.36932/jpcam.v3i2.70\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cayenne pepper leaf (Capsicum frutescents L) is one of the natural ingredients that contains chemical compounds including saponins, alkaloids, terpenoids, quinones and flavonoids. Saponin and flavonoid compounds in cayenne pepper leaves have a role to stimulate hair growth. So that it can be used to overcome the problem of hair loss, where hair loss often occurs in the community dueto lack of nutritional intake and excessive use of chemicals. To overcome this, this research was carried out which aims to use preparations from natural ingredients of ethanol extract of cayenne pepper leaves which were made into hairtonic preparations with variations of propylene glycol and 96% ethanol Hairtonic formulations used 96% ethanol, menthol, propylene glycol, methyl paraben, propyl paraben, and aquades. Then a physical stability test was carried out to determine at what concentration the hairtonic preparation produced good physical stability. Hairtonic physical stability test was carried out for 14 days of storage with organoleptic results. Brownish orange color in the form of a clear solution and distinctive aroma of cayenne pepper leaf extract, the pH test was from the last cycle Formulation 1: 4.9 then Formulation 2: 5.0 and Formulation 3. : 5.1. Still in the skin pH range of 4.5-6.5, the Viscosity test is from the last cycle of Formulation 1: 1.01 Cps then Formulation 2: 0.95 Cps and Formulation 3: 1.06 Cps. Still in the hair tonic viscosity specification, which is below 5 Cps, in the Specific Gravity test in Formulation 1: 0.9950 gram/ml. then Formulation 2: 0.9951 gram/ml. and Formula 3: 0.9978 gram/ml. Still in the hair tonic viscosity specification, which is ±1 gram/ml. From these results, it can be seen that at concentrations of propylene glycol 10%, 15%, 20% and ethanol 5%, 10%, 15% produced good physical stability\",\"PeriodicalId\":433767,\"journal\":{\"name\":\"Journal of Pharmaceutical Care Anwar Medika\",\"volume\":\"108 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmaceutical Care Anwar Medika\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36932/jpcam.v3i2.70\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmaceutical Care Anwar Medika","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36932/jpcam.v3i2.70","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
辣椒叶(Capsicum frutescents L)是一种含有皂苷、生物碱、萜类、醌类和黄酮类化合物的天然成分。辣椒叶中的皂苷和类黄酮化合物有促进头发生长的作用。因此,它可以用来克服脱发的问题,在社区中,由于缺乏营养摄入和过度使用化学品,经常发生脱发。为了克服这一问题,本研究的目的是利用辣椒叶乙醇提取物的天然成分制成的制剂,用丙二醇和96%乙醇制成滋补剂。滋补剂配方使用96%乙醇、薄荷醇、丙二醇、对羟基苯甲酸甲酯、对羟基苯甲酸丙酯和水基化合物。然后进行了物理稳定性试验,以确定在何种浓度下发胶制剂具有良好的物理稳定性。对其进行了14 d的物理稳定性试验,并获得了感官结果。辣椒叶提取物呈棕黄色,溶液清澈,香气独特,pH值从配方1:4.9依次为配方2:5.0和配方3。: 5.1。仍在皮肤pH值为4.5-6.5的范围内,粘度测试是从配方1:1.01 Cps,然后是配方2:0.95 Cps和配方3:1.06 Cps的最后一个循环开始。在配方1的比重试验中:0.9950克/毫升,仍在护发液粘度规格中,低于5cps。则配方2:0.9951 g /ml。式3:0.9978 g /ml。仍在养发粘度规格,即±1克/毫升。从这些结果可以看出,在丙二醇浓度为10%、15%、20%和乙醇浓度为5%、10%、15%时产生了良好的物理稳定性
Formulasi dan Uji Stabilitas Fisik Sediaan Hair Tonic Ekstrak Daun Cabai Rawit (Capsium Frutescent L). Dengan Variasi Propilenglikol Dan Etanol 96%
Cayenne pepper leaf (Capsicum frutescents L) is one of the natural ingredients that contains chemical compounds including saponins, alkaloids, terpenoids, quinones and flavonoids. Saponin and flavonoid compounds in cayenne pepper leaves have a role to stimulate hair growth. So that it can be used to overcome the problem of hair loss, where hair loss often occurs in the community dueto lack of nutritional intake and excessive use of chemicals. To overcome this, this research was carried out which aims to use preparations from natural ingredients of ethanol extract of cayenne pepper leaves which were made into hairtonic preparations with variations of propylene glycol and 96% ethanol Hairtonic formulations used 96% ethanol, menthol, propylene glycol, methyl paraben, propyl paraben, and aquades. Then a physical stability test was carried out to determine at what concentration the hairtonic preparation produced good physical stability. Hairtonic physical stability test was carried out for 14 days of storage with organoleptic results. Brownish orange color in the form of a clear solution and distinctive aroma of cayenne pepper leaf extract, the pH test was from the last cycle Formulation 1: 4.9 then Formulation 2: 5.0 and Formulation 3. : 5.1. Still in the skin pH range of 4.5-6.5, the Viscosity test is from the last cycle of Formulation 1: 1.01 Cps then Formulation 2: 0.95 Cps and Formulation 3: 1.06 Cps. Still in the hair tonic viscosity specification, which is below 5 Cps, in the Specific Gravity test in Formulation 1: 0.9950 gram/ml. then Formulation 2: 0.9951 gram/ml. and Formula 3: 0.9978 gram/ml. Still in the hair tonic viscosity specification, which is ±1 gram/ml. From these results, it can be seen that at concentrations of propylene glycol 10%, 15%, 20% and ethanol 5%, 10%, 15% produced good physical stability