软骨发育不全的黄韧带骨化表现为背侧脊髓病的罕见病例

Tamajit Chakraborty, D. Sharma, A. Goyal, V. Madan
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引用次数: 4

摘要

黄韧带骨化(OLF)由Polgar发现,并由Yamaguchi和Isuruni进一步描述[1]。在胸椎脊髓病中,其发病率低于后纵韧带骨化症(OPLL),高于髓核突出症(HNP)[1]。它主要流行于日本和其他东亚国家,如韩国和中国[2]。软骨发育不全是一种骨骼生长的遗传性疾病,先天性椎管狭窄是一种众所周知的并发症[3]。脊柱退行性改变,如椎间盘突出、退行性颈椎病和关节病,可导致狭窄加重[4]。然而,软骨发育不全患者因黄韧带骨化而出现症状性椎管狭窄的情况极为罕见[5,6]。我们提出一个罕见的病例椎管狭窄由于骨化的黄韧带在30岁的印度女性软骨发育不全表现为背脊髓病。
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A Rare Case of Ossification of Ligamentum Flavum presenting as Dorsal Myelopathy in Achondroplasia
Ossification of the ligamentum flavum (OLF) was discovered by Polgar and further described by Yamaguchi and Isuruni [1]. Among the thoracic myelopathies, its incidence is less than that of ossification of the posterior longitudinal ligament (OPLL) and higher than that of herniated nucleus pulposus (HNP) [1]. It is mostly prevalent in Japan and other East Asian countries such as Korea and China [2]. Achondroplasia is a genetic disorder of bone growth with congenital spinal stenosis being a well known complication [3]. Degenerative changes of the spine, such as disc herniation, degenerative spondylosis and arthrosis result in worsening of stenosis [4]. However, symptomatic spinal stenosis due by ossification of the ligamentum flavum (OLF) in achondroplasia is extremely rare [5,6]. We present a rare case of spinal stenosis due to ossified ligamentum flavum in a 30 year old Indian female of achondroplasia presenting as dorsal myelopathy.
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