[细胞学研究在泌尿学中的作用]。

U Maier, N Neuhold
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引用次数: 0

摘要

对1100例前列腺、尿路上皮及淋巴结病理发现的患者行细胞学检查并进行组织学对照。前列腺细胞学检测肿瘤的灵敏度为81%。通过重新评估最初的假阴性或仅可疑的抽吸,特异性率达到90%,而不满意的涂片率增加了一倍。在尿路上皮肿瘤中,冲洗细胞学的证据明显高于剥脱细胞学,并取决于肿瘤的分级和分期。低恶性程度的肿瘤很少被细胞学检测到。局部化疗似乎改变了细胞学检查的准确性,因为很难将恶性肿瘤相关的细胞变化与治疗诱导的细胞特征分开。腹膜后淋巴结经腹膜穿刺细胞学检查无证据。
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[The role of cytological studies in urology].

1100 patients with pathological findings of the prostate, urothelium and lymph-nodes underwent cytological examination with histological control. Prostatic cytology showed a sensitivity of 81% in detecting cancer. Through reassessment of originally false negative or only suspicious aspirates a specificity rate of 90% was achieved while the rate of unsatisfactory smears were doubled. In urothelial tumors evidence of lavage cytology was significantly higher than exfoliative cytology and depends on grading and staging of the tumor. Tumors with a low grade of malignancy were rarely detected cytologically. Topical chemotherapy seems to change the accuracy of cytological examinations because of the difficulty to separate malignancy associated cell changes from therapy induced cellular features. Transperitoneal aspiration cytology of retroperitoneal lymph-nodes has no evidence.

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