益生菌鉴定用16S rRNA基因及其片段的研究

Amar Čosić, Altijana Hromic Jahjefendic
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引用次数: 0

摘要

16s-rRNA由高变区(V1 - V9)组成,在不同的细菌中显示出相当大的序列多样性。在给定的高变区域内的物种特异性序列构成诊断分析和其他科学研究的有用靶标。通常基因区域的大小为1500bp,这是足够大的,可以使用生物信息学工具进行分析并应用于检测。提高对细菌菌株中16s-rRNA基因片段的认识,将有助于更好地理解和更好地诊断细菌菌株。这也可作为病原微生物调查的基础。
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Investigation Of 16S rRNA Gene And Gene Segments For The Determination Of Probiotics
The 16s-rRNA consists of hypervariable regions (V1 – V9) that demonstrate considerable sequence diversity among different bacteria. Species-specific sequences within a given hypervariable region constitute useful targets for diagnostic assays and other scientific investigations. Usually the size of the gene region is 1500 bp, which is large enough to be analyzed using bioinformatic tools and applied for detection. The need to advance the knowledge of the 16s-rRNA gene segments in bacterial strains would allow better understanding and better diagnostic possibilities when dealing with them. This could also be the basis for investigation of pathogenic microorganisms.
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