使用环丙沙星成功根除人类免疫缺陷病毒感染者因中国弯曲杆菌引起的菌血症。

L V Sacks, A M Labriola, V J Gill, F M Gordin
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引用次数: 36

摘要

男同性恋者,36岁,感染人类免疫缺陷病毒,有2个月发热和间歇性腹泻史。粪便培养对细菌病原体、虫卵、寄生虫和抗酸生物均呈阴性。最初的血培养在5天后呈阳性,为弯曲的革兰氏阴性棒,后来被确定为中国弯曲杆菌。患者接受了一系列抗生素治疗方案,包括2周的红霉素疗程和2周的四环素疗程,但随访的血液培养继续产生cinaedi。患者随后口服环丙沙星2周疗程;11周后,他仍无症状,当时血培养呈阴性。据我们所知,这是第一例用环丙沙星成功治疗的由cinaedi引起的症状性菌血症病例。
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Use of ciprofloxacin for successful eradication of bacteremia due to Campylobacter cinaedi in a human immunodeficiency virus-infected person.

A 36-year-old homosexual man who was infected with human immunodeficiency virus presented with a 2-month history of fever and intermittent diarrhea. Stool cultures were negative for bacterial pathogens, ova, parasites, and acid-fast organisms. An initial blood culture became positive after 5 days for a curved, gram-negative rod that was identified later as Campylobacter cinaedi. The patient received a series of antibiotic regimens, including a 2-week course of erythromycin followed by a 2-week course of tetracycline, but follow-up blood cultures continued to yield C. cinaedi. The patient was then treated with a 2-week course of oral ciprofloxacin; he remained asymptomatic 11 weeks later, at which time a blood culture was negative for C. cinaedi. To the best of our knowledge, this is the first documented case of symptomatic bacteremia due to C. cinaedi that was successfully treated with ciprofloxacin.

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