神经妥乐平的抗痛觉和选择性镇痛作用。

Farmakologiia i toksikologiia Pub Date : 1991-07-01
S V Litvinova, V V Aristova, A L Kaliuzhnyĭ, V V Shul'govskiĭ, L V Kaliuzhnyĭ
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引用次数: 0

摘要

在白化病大鼠的实验中,神经妥乐平注射增加了痛觉性热刺激下甩尾试验的潜伏期,而不改变痛觉性皮肤电刺激下甩尾试验的阈值。内啡肽抗血清的管理降低阈值和潜伏期的甩尾试验,以响应这两种刺激。初步给予神经妥乐平可降低抗血清对两种伤害性刺激的过敏作用。
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[The antihyperalgesic and selective analgesic effects of neurotropin].

In experiments of albino rats neurotropin injection was shown to increase the latency of the tail-flick test in response to the nociceptive thermal stimulus and didn't change the threshold of the test in response to the nociceptive electroskin stimulus. The administration of the antiserum to beta-endorphin lowered the threshold and the latency of the tail-flick test in response to both stimuli. The preliminary administration of neurotropin reduced the hyperalgesic effect of the antiserum on both nociceptive stimuli.

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