[细胞化学研究碱性磷酸酶活性作为浆液膜衬里腔渗出物的癌细胞标志物]。

Vrachebnoe delo Pub Date : 1991-12-01

I V Abramenko, A I Evsev'eva, G V Pisniachevskaia

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引用次数: 0

摘要

细胞化学证明左旋咪唑敏感碱性磷酸酶(AP)已被用于浆液积液中肿瘤细胞的鉴定。18例非癌症患者浆液中间皮细胞和组织细胞-巨噬细胞未发现ap活性。在52例癌症患者的19例浆液中检测到癌细胞中的酶活性。肿瘤相关抗原在ap阳性癌细胞的细胞膜上被检测到比ap阴性癌细胞更罕见。

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[Cytochemical study of alkaline phosphatase activity as a cancer cell marker in exudates from serous-membrane lined cavities].

Cytochemical demonstration of levamisole-sensitive alkaline phosphatase (AP) have been used for the identification of tumor cells in serous effusions. AP-activity is not demonstrable in mesothelial cells and histiocytes-macrophages in serous effusions in 18 noncancer patients. Enzyme activity is detected in cancer cells in serous effusions in 19 from 52 cancer patients. Oncoassociated antigens are detected on the membranes of AP-positive cancer cells more rare that AP-negative cancer cells.

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