药物在蚂蚁模型上的副作用研究:综述

M. Cammaerts
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引用次数: 1

摘要

到目前为止,我们以蚂蚁为模型,研究了人类使用的47种产品的副作用,在这些研究中,我们发表了五份主要发现的摘要。在那之后,我们研究了人类使用的其他六种药物的副作用,我们在这里总结这些最后得到的结果。这六种药物分别是右美沙芬、阿米替林、艾司西酞普兰、氟伏沙明、依维菌素和吲达帕胺。对于每一种药物,我们都发现了与人类相似的副作用,但我们也观察到尚未提到的人类副作用。它们主要涉及运动,活动,感官知觉,社会关系和学习。从业人员和药师应重视我们的工作,以更充分和安全地使用我们检查的六种药物。我们的六部作品已经出版,因此可以使用,但它们也可以由作者提供。在我们所有的研究中,蚂蚁似乎是优秀的生物模型;这些实验可以简单、快速、成本低廉地进行,同时提供具有统计学意义的结果。
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Side effects of drugs studied on ant models: a mini review
Using ants as models, we studied until now the side effects of 47 products used by humans and, over these studies we published five summaries of our main findings. After that, we studied the side effects of six other drugs used by humans, and we here summarize these lastly obtained results. These six other drugs were dextromethorphan, amitriptylin, escitalopram, fluvoxamine, iverectin, and indapamide. For each of them, we found side effects similar to those reported for humans, but we also observed side effects not yet mentioned for humans. They concerned among others the locomotion, the activity, the sensory perception, the social relationships and the learning. Practitioners and pharmacists should take cognizance of our works for more adequately and safely used the six drugs we examined. Our six works are published and thus available, but they can also be provided by the author(s). All over our studies, ants appeared to be excellent biological models; the experiments could be made easily, rapidly and at lost cost, while providing statistically significant results.
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