[Proper-Myl影响下慢性淋巴白血病患者外周血淋巴细胞与中性粒细胞体液相互作用的特点]。

Vrachebnoe delo Pub Date : 1991-10-01
L M Tishchenko, S A Guseva, A A Fed'ko
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引用次数: 0

摘要

一项对32例慢性淋巴细胞增多症(CL)患者的研究显示,吞噬中性粒细胞数量减少,淋巴细胞产生的刺激粒细胞吞噬功能的体液介质减少。结果表明,通常使用的细胞抑制剂处理对研究值没有本质影响。在慢性淋巴细胞增多症患者的治疗过程中加入proper-myl进一步增加了吞噬中性粒细胞的数量,并增加了刺激粒细胞吞噬活性的体液介质的产生。
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[The characteristics of the humoral interaction of lymphocytes with neutrophilic granulocytes of the peripheral blood in patients with chronic lympholeukemia under the influence of Proper-Myl].

A study of 32 patients with chronic lympholeucosis (CL) revealed a reduction of the number of phagocytosing neutrophil granulocytes and a reduction of production of humoral mediators by lymphocytes that stimulated the phagocytic function of granulocytes. It is shown that treatment by usually used cytostatic agents did not essentially effect the investigated values. Inclusion of proper-myl in the treatment course of patients with chronic lympholeucosis furthered increase of the number of phagocytosing neutrophil granulocytes and an increased production of humoral mediator stimulating the phagocytic activity of granulocytes.

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