[药理学中的核磁共振]。

Farmakologiia i toksikologiia Pub Date : 1991-11-01
I S Chekman, N A Gorchakova, T G Samarskaia
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引用次数: 0

摘要

核磁共振波谱在研究溶液中快速过程、复杂形成和代谢反应的结构、动力学和热力学方面具有其他技术所无法比拟的优势。核磁共振用于研究生物活性物质和药物的结构,它们的作用机制,因为它允许建立分子中单核的化学位移,自旋-自旋相互作用的常数,弛豫时间。
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[Nuclear magnetic resonance in pharmacology].

The NMR spectroscopy has advantages over other techniques in studying the structure, kinetics and thermodynamics of rapid processes, complex formation and metabolism reactions in the solution. NMR is used for investigating the structure of biologically active substances and drugs, the mechanism of their action as it permits the establishment of chemical shifts of single nuclei in the molecule, the constants of spin-spin interaction, the time of relaxation.

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[An analysis of the age-related characteristics of the analgesic action of clofelin]. [Neuroendocrine and immunological interactions in chronic alcoholism]. [The history of the Department of Pharmacology of the Kiev Medical Institute]. [The genetically determined polymorphism of metabolic oxidation of the sparteine-debrisoquin type]. [Nuclear magnetic resonance in pharmacology].
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