[帕米胺在肝脏毒性病变中的抗氧化特性]。

Farmakologiia i toksikologiia Pub Date : 1991-11-01
A N Riabkov, D G Uzbekova, G B Artem'eva, A A Nikulin
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引用次数: 0

摘要

对四氯甲烷致肝毒性损伤大鼠的实验表明,帕米啶(吡啶氨基脲)可促进肝组织匀浆和红细胞脂质过氧化活性的降低。自由基氧化正常化的明显趋势与肝脏组织学图像的积极动态相关。
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[The antioxidant properties of parmidine in a toxic lesion of the liver].

The experiments on rats with toxic lesions of the liver induced by tetrachlorinemethane showed that parmidine (pyridinolcarbamat) promotes the reduction of the activity of lipid peroxidation in the liver tissue homogenates and erythrocytes. The pronounced tendency towards normalization of free-radical oxidation correlated with the positive dynamics of the histological picture of the liver.

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