从膀胱肿瘤患者受刺激淋巴细胞中分离出一株感染性致癌腺病毒。

Acta microbiologica Hungarica Pub Date : 1991-01-01
G Kulcsár, S Csata, I Nász
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引用次数: 0

摘要

为了从肿瘤细胞和循环淋巴细胞中培养病毒,我们从一名膀胱肿瘤患者的植物血凝素刺激的外周血t淋巴细胞中分离出一种致瘤性感染性腺病毒18型毒株。病毒基因组被认为与其他DNA病毒和受损的免疫系统相互作用,在肿瘤的发展中起一定的作用。
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Isolation of an infectious oncogenic adenovirus strain from the stimulated lymphocytes of a patient with bladder tumour.

In attempts to grow viruses from tumour cells and circulating lymphocytes, we isolated an oncogenic infectious adenovirus type 18 strain from the phytohaemagglutinin-stimulated peripheral T-lymphocytes of a patient with bladder tumour. The virus genome is assumed to play certain role in the development of the tumour in interaction with other DNA viruses and the damaged immune system.

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