金银花(密)B.L.罗布:医药用途和化学生物学潜力综述

M. A. Jiménez-Arellanes
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引用次数: 0

摘要

药用植物是化学结构的储存库,具有丰富的生物活性,具有重要的经济价值。世界上80%以上的人口都在使用这些植物,因此这些植物被过度开发,因为它们是主要药物(紫杉醇、吗啡、长春新碱、长春花碱、青蒿素、galegin等)的来源,而且具有很高的营养、木材、化妆品和/或农业价值。目前,中国出口MP 12万吨,印度约3.2万吨,欧洲进口40万吨;这种过度开发导致许多植物濒临灭绝。同时,MP也是人参、海百利康、紫锥菊、卡瓦卡瓦、维果、Plantival、Prostasan等植物药的原料,其疗效和安全性已得到科学的验证。在墨西哥传统医学中广泛使用圆锥砖,但从化学和生物学角度对其研究甚少;本文对该药用植物的生物化学报道进行了综述。
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Brickellia paniculata (Mill.) B.L. Rob: A Review of Medicinal Uses and Chemo-Biological Potential
Medicinal plants (MP) are a reservoir of chemical structures and have great economic importance due to their diverse biological activities. These are used by more than 80% of the world population, for this reason these are overexploited because they are a source of main drug (taxol, morphine, vincristine, vinblastine, artemisinin, galegin, etc.), and also have high nutritional, timber, cosmetic, and/or agricultural value. At present, China exports 120,000 tons of MP, India about 32,000 tons while Europe imports 400,000 tons; this overexploitation has caused many of these plants to be in danger of extinction. Also, MP are raw material for the development of phytodrugs such as Ginseng, Hyperikan, EchinaceA, Kava-kava, Vitango, Plantival, Prostasan among others, whose therapeutic efficacy and safety has been scientifically assayed. Brickellia paniculata is widely used in Mexico in traditional medicine, and has been poorly investigated from the chemical and biological point of view; so in this paper we describe the biological and chemical reports for this medicinal plant.
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