Childhood Alopecia Totalis: A Case and A Concise Review of The Available Evidence-Based Therapies.

Abstract In the modern medical literature, alopecia totalis has been reported as early as the 1940s. Childhood alopecia totalis is a heterogeneous disorder that occur in syndromic and non-syndromic forms and can have autoimmune, nutritional and genetic bases. Non-syndromic childhood alopecia totalis is generally has autoimmune bases. During the 1970s, authors reported the treatment of alopecia totalis with DNCB which is 1-chloro, 2, 4-dinitrobenzene and High-dose glucocorticoid. Early during the 1980s, oral photochemotherapy was used in the treatment of alopecia totalis without the occurrence of side effects. The aim of this paper is to present a case of childhood non-syndromic alopecia totalis and to review of the available evidence-based therapies.