马尔堡病毒:一种全球性病毒,而不仅仅是非洲的问题

J. Robinson, Indrajit Banerjee, Alexandra Leclézio
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摘要

马尔堡病毒(MBV)在系统发育上属于线状病毒科,其临床表现、传播和毒性与埃博拉病毒非常相似。MBV的显著毒性不仅引起了非洲地区的极大关注,而且引起了整个全球的极大关注,因为最近从处理非洲绿猴的实验室爆发的病毒已迅速蔓延到乌干达、南非、肯尼亚和安哥拉。感染病毒后,患者会出现多种症状,其中出血、癫痫和休克是最严重和最致命的症状。目前还没有药物、疫苗或治疗方法可以对抗病毒的致命进展和过程,因此它经常通过家庭传播,在亲密的亲人之间传播,并最终留下死亡的痕迹。现在最重要的是,为了更大的利益,国际资金、知识和专门知识必须统一起来;开发类似埃博拉病毒和马尔堡病毒的治疗方法和疫苗,不仅是为了保护自己,也是为了保护世界各地的人类。
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Marburgvirus: A Global Virus, not just an African problem
The Marburg virus (MBV) phylogenetically belongs to the filovirus family and its clinical picture, spread and virulence resemble the Ebola virus very closely. The marked virulence of MBV is of great concern for not only the African region, but the globe in its entirety as a recent outbreak of the virus from a lab handling African green monkeys has rapidly spread to Uganda, South Africa, Kenya and Angola. On contamination of the virus the individual develops a plethora of symptoms with haemorrhage, seizures and shock being the most profound and deadly. No drug nor vaccine or cure is available against the deadly progression and course of the virus, and thus it often disseminates through households, between close loved ones and ultimately leaving a trail of death in its wake. It is now of upmost importance that international funding, knowledge and expertise become unified for the greater good; to develop treatments and vaccines to such viruses a likened to Ebola and Marburg virus to not only protect oneself, but humanity across all boarders around the world.
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