[胆石症患者的细胞-体液免疫因子无并发和并发炎症过程]。

Vutreshni bolesti Pub Date : 1991-01-01
D Petrova, A Mikhaĭlova, V Kolarski
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引用次数: 0

摘要

用Becton-Dickinson公司的单克隆抗体对82例患者进行了检测,其中10例为单纯胆石症患者,8例为慢性结石性胆囊炎患者,34例为胆总管结石合并狭窄性乳突-乳突炎患者。检测以下免疫活性细胞克隆和亚克隆:CD3+、CD16+、CD4+、CD8+、CD19+ CD4/CD8、HLA-DR+、CD3+。用荧光标记活化细胞克隆分析仪“FACS-TAR”读取结果。同时检测血清IgA、IgM、IgG、C3-C4补体分数和循环免疫复合物。分析结果表明,在胆管炎症过程的复杂病例中,多种体液和细胞免疫因子参与了胆管炎症过程。
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[The cellular-humoral immune factors of patients with cholelithiasis uncomplicated and complicated by an inflammatory process].

82 patients-10 p. with uncomplicated cholelithiasis, 8 p. with chronic calculous cholecystitis, 34 p. with choledocholithiasis with stenosing papillo-odditis--and 30 healthy controls were examined, with monoclonal antibodies of the firm "Becton-Dickinson". The following immunocompetent cellular clones and subclones were examined: CD3+, CD16+, CD4+, CD8+, CD19+ CD4/CD8, HLA-DR+, CD3+. The results were read with analyzer for fluorescently marked activated cell clones "FACS-TAR". The serum IgA, IgM, IgG, C3-C4 complement fractions and circulating immune complexes were also examined. The analysis of the results shows that in the complicated cases of cholelithiasis with an inflammatory process in the biliary ducts several humoral and cellular immune factors take part.

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