M Böck, L Greither, A Gudden, H Diehm, M U Heim, W Mempel
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[Storage of thrombocyte concentrates: ultrastructural and functional changes].
Optimal storage of platelet concentrates is still an unsolved problem. The present paper demonstrates changes in morphology and function of stored platelets. Transmission microscopy reveals a loss of organelles as well as a progredient destruction of cell membranes during storage. At the same time in vitro aggregability is clearly diminished. Therefore, further investigations seem to be necessary to improve storage conditions of platelets.