肥胖与前列腺癌:代谢综合征的影响

Ghassan Salibi
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引用次数: 0

摘要

肥胖是公共健康的一个重大问题,它与包括癌症在内的多种慢性疾病有关。前列腺癌是男性中最常见的疾病,越来越多的证据表明肥胖可能会影响前列腺癌的风险和预后。本文回顾了目前关于肥胖与前列腺癌之间联系的科学知识,强调了代谢综合征的参与。该研究调查了肥胖和前列腺癌风险之间存在直接关系的证据,以及这种联系背后可能的过程,如激素、免疫调节和代谢途径的改变。此外,它还研究了代谢紊乱的影响,包括胰岛素抵抗和代谢综合征。
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Obesity and prostate cancer: the influence of metabolic syndromes
Obesity is a significant issue for public health that is linked to a variety of chronic ailments, including cancer. Prostate cancer is the most frequent disease in men, and there is growing evidence that obesity might impact prostate cancer risk and prognosis. This article reviews the present body of scientific knowledge on the link between obesity and prostate cancer, emphasizing the involvement of metabolic syndromes. It examines the evidence indicating a direct relationship between obesity and prostate cancer risk and the likely processes behind this link, such as alterations in hormonal, immune-modulatory, and metabolic pathways. Furthermore, it investigates the influence of metabolic disorders, including insulin resistance and metabolic syndrome.
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