水提物抗溃疡机制的研究

Dinesh Babu J, Akila CR, Sravan Kumar P, Vinaya B
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摘要

消化性溃疡疾病,也被称为溃疡,是当今世界上最引人注目的疾病。20-50岁年龄组的人是受溃疡疾病影响的一大群体。这种疾病本身并不可怕,但它会导致身体中的许多其他问题和疾病。这可能是由于多种因素造成的,比如长期使用强效药物,比如非甾体抗炎药,营养不足,以及不健康的生活习惯,比如吸烟、压力等。草药被用来治疗许多疾病,世界上近50%的人口使用草药。药用植物是治疗这些疾病的主要来源。许多植物已经研究和调查了抗溃疡的特性,在这方面也发表了各种出版物。采用乙醇诱导溃疡病的方法,提取四叶蛇耳草(Osyris quadripartite)水提物,研究其抗溃疡活性。这些提取物分三种剂量进行测试,并与标准药物奥美拉唑进行比较。与低剂量和标准药物相比,高剂量的提取物表现出更显著的活性。
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Anti-ulcer mechanism of the aqueous extract of Osyris quadripartite
Peptic ulcer disease, otherwise called as Ulcers, is the most noted disease in the world today. A large population that is affected with the ulcer disease is the age group of people between 20-50 years of age. This disease is not dreadful on its own but is responsible for the causation of many other problems and diseases in the body. This may be due to various factors like the long-term usage of potent drugs like NSAID's, nutrition deficiencies, and unhealthy lifestyle habits like smoking, stress etc. Herbs are being used to treat many diseases, and almost 50% of the population in the world uses herbal-based medicine. Medicinal plants are the primary sources of a cure for those diseases. Numerous plants have been researched and investigated for the anti-ulcer property, and various publications were made too in this respect. Aqueous extract of the plant, Osyris quadripartite was extracted and investigated for the anti-ulcer activity in the ethanol-induced ulcer disease method. The extracts were tested in three doses and compared to the standard drug, Omeprazole. The extract at a higher dose exhibited more significant activity when compared to that at a lower dose and also the standard drug.
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