免疫校正背景下公猪阉割期间血液学参数的动态变化

V. Reshetnyak, A. Stekolnikov, V. Burdeyniy, L. Malakhova
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摘要

养猪是肉制品生产的主要农业产业之一。阉割是一种有助于提高动物生产力和调节肉质量的技术(消除“野猪肉的气味”)。其缺点是存在阉割后并发症。减少它们数量的有效方法是使用具有免疫效应的药物。因此,我们进行了该药物组代表之一(timogen)对公猪去势期间血液学参数动态的影响试验。血液学研究的数据(在实验期间)表明体内平衡的破坏,表现在阉割后的头14天,出现贫血(红细胞和血红蛋白数量减少)和血小板减少,这(与红细胞减少一样)是在细胞异位的背景下记录的。同时,由于淋巴细胞的绝对数量和相对数量以及中型细胞(MID)的绝对数量,结果反映了白细胞的图像,表明炎症过程伴随着白细胞增多。观察第30天,红细胞和血红蛋白数量较第14天有所增加,血小板和白细胞减少。因此,用5天疗程的铁原进行免疫矫正,可以抵消手术干预对造血的负面影响,这使我们能够避免红细胞和白细胞形态组成的急剧波动。
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Dynamics of hematological parameters during castration of boars on the background of immunocorrection
Pig breeding is one of the leading farm industries for the production of meat products. Castration is one of the techniques that help to increase the productivity of animals and regulate the quality of meat (eliminating the “smell of boar meat”). Its disadvantage is the presence of post-castration complications. An effective method of reducing their number is the use of drugs that have an immunotropic effect.Therefore, we conducted an experiment to find out the effect of one of this drug group representatives (timogen) on the dynamics of hematological parameters during castration of boars.The data of hematological studies (during the experiment) signified a violation of homeostasis, manifested in the first fourteen days after castration by the development of anemia (a decrease in the number of erythrocytes and hemoglobin) and thrombocytopenia, which (like erythropenia) was recorded against the background of anisocytosis. At the same time, the results, reflecting the picture of white blood, indicated an inflammatory process accompanied by leukocytosis, due to both the absolute and the relative number of lymphocytes, as well as the absolute number of medium-sized cells (MID). On the 30th day of observation, an increase in the number of erythrocytes and hemoglobin relative to the 14th day was noted against the background of a decrease in platelets and leukopenia.Thus, immunocorrection with a five-day course of timogen made it possible to neutralize the negative effect of surgical intervention on hematopoiesis, which allowed us to avoid sharp fluctuations in the morphological composition of red and white blood.
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