异丁酸睾酮对性腺功能低下男性替代治疗期间血清脂蛋白的影响。

Czechoslovak medicine Pub Date : 1991-01-01

V Hána, J Marek, R Ceska, J Sobra, R Hampl, L Stárka

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引用次数: 0

摘要

性腺功能低下的男性用异丁酸睾酮替代治疗，每两周100毫克静脉注射一次，不会导致脂蛋白谱的永久性显著改变，也不会增加立体发生的风险。在雄激素作用下肝脏脂肪酶活性和脂蛋白谱的预期变化明显被雄激素转化形成的雌激素的拮抗作用所抑制。

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Influence of testosterone isobutyrate on serum lipoproteins during replacement therapy of hypogonadal men.

Replacement therapy of hypogonadal men with testosterone isobutyrate, 100 mg by the i.m. route every two weeks, does not lead to a permanent significant change of the lipoprotein spectrum and to an increased risk of stereogenesis. The expected changes in the liver lipase activity and in the lipoprotein spectrum under the influence of the administered androgens are obviously suppressed by the antagonistic action of estrogens formed by conversion from androgens.

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Czechoslovak medicine

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