嵌合小鼠视网膜色素上皮内克隆细胞分布分析。

N A Malinina, E G Marchuk
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引用次数: 0

摘要

测定10只新生和5只20日龄聚集嵌合小鼠视网膜色素上皮(RPE)中色素细胞和非色素细胞的数量C/C---- C/C。父本基因型的细胞比例在整个左右眼RPE或其单独区域(即背、中、腹)均表现出较强的相关性。RPE细胞克隆呈随机分布。RPE色素细胞的数量与被毛色素沉着的百分比呈高度相关。
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[An analysis of the distribution of clone cells in the retinal pigment epithelium from chimeric mice].

The quantity of pigmented and unpigmented cells was estimated in the retinal pigment epithelium (RPE) in ten newborn and five 20-days old aggregated chimaeric mice C/C----c/c. A strong correlation was shown in the proportion of cells of the paternal genotypes either in the whole RPE of right and left eyes or in its separate regions, i.e. dorsal, central, ventral. Random distribution was revealed in these RPE cells clones. A high correlation was shown between the number of RPE pigmented cells and percentage of coat pigmentation.

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