创伤后应激障碍治疗研究综述与评价

J. Hamblen, E. Barnett, Barbara A. Hermann, P. Schnurr
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引用次数: 2

摘要

本章概述了设计和评估临床试验的关键概念,重点是PTSD的随机对照试验。第一部分讨论设计元素以及它们如何影响可以从研究中得出的结论。从创伤文献的例子提供时,可用来说明概念。第二部分探讨创伤后应激障碍治疗试验的最新进展。具体来说,它讨论了与PTSD常见合并症有关的治疗和设计考虑,适应低资源环境的治疗和优化治疗结果。本章的目标是提高临床医生和研究人员对PTSD临床试验进行批判性审查的能力。
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PTSD Treatment Research: An Overview and Evaluation
This chapter provides an overview of key concepts in designing and evaluating clinical trials, with a focus on randomized controlled trials for PTSD. The first section discusses design elements and how they influence the conclusions that can be drawn from a study. Examples from the trauma literature are provided when available to illustrate concepts. The second section explores newer developments in PTSD treatment trials. Specifically, it discusses treatment and design considerations related to common comorbid conditions of PTSD, adapting treatments for low-resource environments and optimizing treatment outcome. The chapter’s goal is to improve the ability of both clinicians and researchers to critically review PTSD clinical trials.
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