[单侧肾切除术和不同剂量二丁基亚硝胺应用后大鼠尿路上皮的增殖动力学——单肾状态在致癌作用中的一个例子]。

Acta histochemica. Supplementband Pub Date : 1990-01-01
F Theuring, C Balint, W Meier
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引用次数: 0

摘要

我们观察了单侧肾切除术后大鼠肾细胞的增殖和不同剂量的DBN与饮用水的应用。我们用3h -胸腺嘧啶控制增殖的测量。应用dbn和单侧肾切除术的重要实验结果是:1。肿瘤发病率较高,2。肿瘤出现时间比单纯DBN组早。
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[Proliferation kinetics in rat urothelium after unilateral nephrectomy and various doses of dibutylnitrosamine application--an example of the roles of a one kidney state on carcinogenesis].

We investigated the proliferation of urothel of the rat after unilateral nephrectomy and application of DBN with drinking water in various doses. We controlled the measurement of proliferation with 3H-thymidine. The important results of our experiments with DBN-application and unilateral nephrectomy were: 1. the tumour-incidence is higher and 2. the tumour-appear is earlier than in experiments with only DBN.

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