{"title":"脂多糖(LPS)对IL-1的诱导及合成脂质A前体Ia对其的调节。","authors":"H D Flad","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The synthetic precursor Ia of lipid A (compound 406), lacking dodecanoic and tetradecanoic fatty acids, is inactive in inducing IL-1, but is able to modulate the production and the release of LPS-induced IL-1.</p>","PeriodicalId":18130,"journal":{"name":"Lymphokine research","volume":"9 4","pages":"557-60"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Induction of IL-1 by lipopolysaccharide (LPS) and its modulation by synthetic lipid A precursor Ia.\",\"authors\":\"H D Flad\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The synthetic precursor Ia of lipid A (compound 406), lacking dodecanoic and tetradecanoic fatty acids, is inactive in inducing IL-1, but is able to modulate the production and the release of LPS-induced IL-1.</p>\",\"PeriodicalId\":18130,\"journal\":{\"name\":\"Lymphokine research\",\"volume\":\"9 4\",\"pages\":\"557-60\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lymphokine research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lymphokine research","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Induction of IL-1 by lipopolysaccharide (LPS) and its modulation by synthetic lipid A precursor Ia.
The synthetic precursor Ia of lipid A (compound 406), lacking dodecanoic and tetradecanoic fatty acids, is inactive in inducing IL-1, but is able to modulate the production and the release of LPS-induced IL-1.